Abstract

Our findings suggest that biopsies containing chronic lymphocytic leukemia-type cells, but lacking proliferation centers and with non-enlarged or only slightly enlarged lymph nodes on imaging, represent a very indolent disease that may best be considered a tissue equivalent of monoclonal B-cell lymphocytosis rather than overt small lymphocytic lymphoma. We propose that such cases be designated as tissue involvement by chronic lymphocytic leukemia/small lymphocytic lymphoma-like cells of uncertain significance.

Keywords

LymphocytosisMedicineMonoclonalLymphomaImmunologyMonoclonal antibodyVirologyAntibody

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Publication Info

Year
2011
Type
editorial
Volume
96
Issue
8
Pages
1144-1152
Citations
91
Access
Closed

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Sarah Gibson, Steven H. Swerdlow, Judith A. Ferry et al. (2011). Reassessment of small lymphocytic lymphoma in the era of monoclonal B-cell lymphocytosis. Haematologica , 96 (8) , 1144-1152. https://doi.org/10.3324/haematol.2011.042333

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DOI
10.3324/haematol.2011.042333