Abstract

Both AD and FTD patients had increased rates of brain atrophy. Whereas the patients with AD were associated with a relatively restricted spread of atrophy rates, the greater spread of rates observed in the patients with FTD may reflect the heterogeneity of disease in FTD, with differences observed between frontal and temporal FTD. Increased rates of whole-brain atrophy did not discriminate AD from FTD, but analysis of regional atrophy rates revealed marked differences between patient groups.

Keywords

AtrophyFrontotemporal dementiaCerebral atrophyDementiaBrain sizeMedicinePsychologyCerebral cortexCardiologyPathologyInternal medicineMagnetic resonance imagingRadiologyDisease

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Publication Info

Year
2001
Type
article
Volume
57
Issue
10
Pages
1756-1763
Citations
218
Access
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Dennis Chan, Nick C. Fox, Rosemary Jenkins et al. (2001). Rates of global and regional cerebral atrophy in AD and frontotemporal dementia. Neurology , 57 (10) , 1756-1763. https://doi.org/10.1212/wnl.57.10.1756

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DOI
10.1212/wnl.57.10.1756