Ranibizumab versus Verteporfin for Neovascular Age-Related Macular Degeneration

David M. Brown; Peter K. Kaiser; Mark Michels; G. Soubrane; Jeffrey S. Heier; Robert Y. Kim; Judy P. Sy; Susan Schneider

doi:10.1056/nejmoa062655

Abstract

Ranibizumab was superior to verteporfin as intravitreal treatment of predominantly classic neovascular age-related macular degeneration, with low rates of serious ocular adverse events. Treatment improved visual acuity on average at 1 year. (ClinicalTrials.gov number, NCT00061594 [ClinicalTrials.gov].).

Keywords

VerteporfinMedicineRanibizumabMacular degenerationOphthalmologyVisual acuityEndophthalmitisSurgeryBevacizumabChoroidal neovascularizationChemotherapy

MeSH Terms

AgedAged80 and overAngiogenesis InhibitorsAntibodiesMonoclonalAntibodiesMonoclonalHumanizedChoroidal NeovascularizationDouble-Blind MethodFemaleHumansInjectionsMacular DegenerationMaleMiddle AgedPhotochemotherapyPhotosensitizing AgentsPorphyrinsRanibizumabVerteporfinVisual Acuity

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Publication Info

Year: 2006
Type: article
Volume: 355
Issue: 14
Pages: 1432-1444
Citations: 3441
Access: Closed

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APA Style

                            
                                
                                    David M. Brown, 
                                
                                    Peter K. Kaiser, 
                                
                                    Mark Michels
                                
                                et al.
                            
                            (2006). 
                            Ranibizumab versus Verteporfin for Neovascular Age-Related Macular Degeneration. 
                            New England Journal of Medicine
                            , 355
                            (14)
                            , 1432-1444.
                            https://doi.org/10.1056/nejmoa062655
                        

Identifiers

DOI: 10.1056/nejmoa062655
PMID: 17021319

Data Quality

Data completeness: 86%