Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Abstract

The addition of temozolomide to radiotherapy for newly diagnosed glioblastoma resulted in a clinically meaningful and statistically significant survival benefit with minimal additional toxicity.

Keywords

TemozolomideMedicineRadiation therapyConcomitantGlioblastomaAdjuvantAdjuvant radiotherapyOncologyInternal medicineSurgeryCancer research

MeSH Terms

Adrenal Cortex HormonesAdultAgedAntineoplastic AgentsAlkylatingBrain NeoplasmsChemotherapyAdjuvantDacarbazineDisease ProgressionFemaleGlioblastomaHumansMaleMiddle AgedProportional Hazards ModelsRadiotherapyComputer-AssistedSurvival AnalysisTemozolomide

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Publication Info

Year: 2005
Type: article
Volume: 352
Issue: 10
Pages: 987-996
Citations: 20758
Access: Closed

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APA Style

                            
                                
                                    Roger Stupp, 
                                
                                    Warren Mason, 
                                
                                    Martin J. van den Bent
                                
                                et al.
                            
                            (2005). 
                            Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma. 
                            New England Journal of Medicine
                            , 352
                            (10)
                            , 987-996.
                            https://doi.org/10.1056/nejmoa043330
                        

Identifiers

DOI: 10.1056/nejmoa043330
PMID: 15758009

Data Quality

Data completeness: 86%