Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis

M R Law M R Law
2003 BMJ 1,717 citations

Abstract

Statins can lower LDL cholesterol concentration by an average of 1.8 mmol/l which reduces the risk of IHD events by about 60% and stroke by 17%.

Keywords

RosuvastatinPravastatinMedicineAtorvastatinSimvastatinInternal medicineFluvastatinStatinCholesterolLovastatinPlaceboStroke (engine)PitavastatinRosuvastatin CalciumEndocrinology

MeSH Terms

CholesterolLDLCohort StudiesDouble-Blind MethodHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMyocardial IschemiaRandomized Controlled Trials as TopicRisk FactorsStroke

Affiliated Institutions

Related Publications

Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR**STELLAR = Statin Therapies for Elevated Lipid Levels compared Across doses to Rosuvastatin. Trial)

The primary objective of this 6-week, parallel-group, open-label, randomized, multicenter trial was to compare rosuvastatin with atorvastatin, pravastatin, and simvastatin acros...

2003 The American Journal of Cardiology 1382 citations

Publication Info

Year
2003
Type
review
Volume
326
Issue
7404
Pages
1423-0
Citations
1717
Access
Closed

Citation Metrics

1717
OpenAlex
71
Influential
1264
CrossRef

Cite This

M R Law (2003). Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis. BMJ , 326 (7404) , 1423-0. https://doi.org/10.1136/bmj.326.7404.1423

Identifiers

DOI
10.1136/bmj.326.7404.1423
PMID
12829554
PMCID
PMC162260

Data Quality

Data completeness: 86%