Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

Keywords

Progenitor cellBiologyProgenitorNeuroscienceFunctional connectivityCell biologyComputational biologyStem cell

Affiliated Institutions

Related Publications

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

Brent A. Reynolds , Samuel Weiss

Neurogenesis in the mammalian central nervous system is believed to end in the period just after birth; in the mouse striatum no new neurons are produced after the first few day...

1992 Science 5337 citations

Inhibition of Dentate Granule Cell Neurogenesis with Brain Irradiation Does Not Prevent Seizure-Induced Mossy Fiber Synaptic Reorganization in the Rat

Jack M. Parent , Eiji Tada , John R. Fike +1 more

Aberrant reorganization of dentate granule cell axons, the mossy fibers, occurs in human temporal lobe epilepsy and rodent epilepsy models. Whether this plasticity results from ...

1999 Journal of Neuroscience 288 citations

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

John D. Cahoy , Ben Emery , Amit Kaushal +9 more

Understanding the cell–cell interactions that control CNS development and function has long been limited by the lack of methods to cleanly separate neural cell types. Here we de...

2008 Journal of Neuroscience 3104 citations

Subgranular Zone of the Dentate Gyrus of Young Rabbits As a Secondary Matrix

G. Guéneau , Anne-Laure Privat , Jean-Baptiste Drouet +1 more

Cell genesis in the subgranular zone of the dentate gyrus of 2-month-old rabbits has been investigated. After incorporation of tritiated thymidine, electron microscopic autoradi...

1982 Developmental Neuroscience 104 citations

Reactive astrocyte nomenclature, definitions, and future directions

Christine R. Rose , Jeffrey D. Rothstein , Nathalie Rouach +78 more

Reactive astrocytes are astrocytes undergoing morphological, molecular, and functional remodeling in response to injury, disease, or infection of the CNS. Although this remodeli...

2021 Nature Neuroscience 2102 citations

Publication Info

Year: 2015
Type: article
Volume: 89
Issue: 1
Pages: 37-53
Citations: 2324
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

2324

OpenAlex

Cite This

APA Style

                            
                                
                                    Ye Zhang, 
                                
                                    Steven A. Sloan, 
                                
                                    Laura Clarke
                                
                                et al.
                            
                            (2015). 
                            Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse. 
                            Neuron
                            , 89
                            (1)
                            , 37-53.
                            https://doi.org/10.1016/j.neuron.2015.11.013
                        

Identifiers

DOI: 10.1016/j.neuron.2015.11.013