Pulmonary-Artery versus Central Venous Catheter to Guide Treatment of Acute Lung Injury

Abstract

PAC-guided therapy did not improve survival or organ function but was associated with more complications than CVC-guided therapy. These results, when considered with those of previous studies, suggest that the PAC should not be routinely used for the management of acute lung injury. (ClinicalTrials.gov number, NCT00281268.).

Keywords

MedicinePulmonary artery catheterAnesthesiaCentral venous catheterIntensive care unitConfidence intervalDialysis catheterDialysisHemodynamicsRandomized controlled trialShock (circulatory)Acute kidney injuryRenal replacement therapyCatheterPulmonary arteryCrossover studyCardiologySurgeryIntensive care medicineCardiac outputInternal medicine

Related Publications

A Multidisciplinary Community Hospital Program for Early and Rapid Resuscitation of Shock in Nontrauma Patients

Frank Sebat , David W. Johnson , Amjad A. Musthafa +4 more

2005 CHEST Journal 143 citations

Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

Emanuel P. Rivers , Bryant Nguyen , Suzanne Havstad +5 more

Early goal-directed therapy provides significant benefits with respect to outcome in patients with severe sepsis and septic shock.

2001 New England Journal of Medicine 10623 citations

Functional hemodynamic monitoring.

Michael R. Pinsky , Didier Payen

Hemodynamic monitoring is a central component of intensive care. Patterns of hemodynamic variables often suggest cardiogenic, hypovolemic, obstructive, or distributive (septic) ...

2005 Critical Care 356 citations

Current treatment of severe sepsis

İsmail Cinel , R. Phillip Dellinger

2006 Current Infectious Disease Reports 19 citations

Lactate Clearance vs Central Venous Oxygen Saturation as Goals of Early Sepsis Therapy<subtitle>A Randomized Clinical Trial</subtitle>

Alan E. Jones

clinicaltrials.gov Identifier: NCT00372502.

2010 JAMA 1021 citations

Publication Info

Year: 2006
Type: article
Volume: 354
Issue: 21
Pages: 2213-2224
Citations: 974
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Pulmonary-Artery versus Central Venous Catheter to Guide Treatment of Acute Lung Injury

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

974

OpenAlex

Cite This

APA Style

                            
                                
                                    Arthur P. Wheeler, 
                                
                                    Gordon R. Bernard, 
                                
                                    Bruce Thompson
                                
                                et al.
                            
                            (2006). 
                            Pulmonary-Artery versus Central Venous Catheter to Guide Treatment of Acute Lung Injury. 
                            New England Journal of Medicine
                            , 354
                            (21)
                            , 2213-2224.
                            https://doi.org/10.1056/nejmoa061895
                        

Identifiers

DOI: 10.1056/nejmoa061895