Protein kinases — the major drug targets of the twenty-first century?

2002 Nature Reviews Drug Discovery 2,151 citations

Abstract

Once upon a time, universities were ivory towers--or, at least, most people saw them as such. Academics prided themselves on not being influenced by, or answerable to, anyone except the academy, and perceived themselves as free from conflicts of interest arising from relationships with people or institutions outside the walls of the university. None of this holds true today and, as the case of Dr Nancy Olivieri illustrates, universities are facing some difficult times in adjusting to these changes.

Keywords

PhosphorylationKinaseDrugDrug developmentProtein phosphorylationProtein kinase ADrug discoveryPharmacologyDrug targetMedicineComputational biologyBioinformaticsBiologyCell biology

MeSH Terms

DeferiproneEthicsMedicalHumansIron Chelating AgentsMoralsPyridonesThalassemia

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Publication Info

Year
2002
Type
review
Volume
1
Issue
4
Pages
309-315
Citations
2151
Access
Closed

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2151
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4
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1884
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Cite This

Philip Cohen (2002). Protein kinases — the major drug targets of the twenty-first century?. Nature Reviews Drug Discovery , 1 (4) , 309-315. https://doi.org/10.1038/nrd773

Identifiers

DOI
10.1038/nrd773
PMID
12120283

Data Quality

Data completeness: 81%