Primary Prevention of Acute Coronary Events With Lovastatin in Men and Women With Average Cholesterol Levels

Abstract

Lovastatin reduces the risk for the first acute major coronary event in men and women with average TC and LDL-C levels and below-average HDL-C levels. These findings support the inclusion of HDL-C in risk-factor assessment, confirm the benefit of LDL-C reduction to a target goal, and suggest the need for reassessment of the National Cholesterol Education Program guidelines regarding pharmacological intervention.

Keywords

MedicineLovastatinInternal medicinePlaceboCholesterolPercentileTriglycerideNational Health and Nutrition Examination SurveyCoronary artery diseaseCohortEndocrinologyGastroenterologyPopulationPathology

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Publication Info

Year: 1998
Type: article
Volume: 279
Issue: 20
Pages: 1615-1615
Citations: 5259
Access: Closed

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APA Style

                            
                                
                                    John R. Downs, 
                                
                                    Michael Clearfield, 
                                
                                    Stephen E. Weis
                                
                                et al.
                            
                            (1998). 
                            Primary Prevention of Acute Coronary Events With Lovastatin in Men and Women With Average Cholesterol Levels. 
                            JAMA
                            , 279
                            (20)
                            , 1615-1615.
                            https://doi.org/10.1001/jama.279.20.1615
                        

Identifiers

DOI: 10.1001/jama.279.20.1615