Predicting a Human Gut Microbiota’s Response to Diet in Gnotobiotic Mice

Abstract

Model microbial communities in mouse guts respond quickly and predictably to dietary shifts.

Keywords

BiologyGut floraMicrobiologyPhysiologyImmunology

Affiliated Institutions

Washington University in St. Louis US

Related Publications

The Effect of Diet on the Human Gut Microbiome: A Metagenomic Analysis in Humanized Gnotobiotic Mice

Peter J. Turnbaugh , Vanessa K. Ridaura , Jeremiah J. Faith +3 more

A translational medicine pipeline is described where human gut microbial communities and diets are re-created in gnotobiotic mice and the impact on microbe and host is defined u...

2009 Science Translational Medicine 3009 citations

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

Carlotta De Filippo , Duccio Cavalieri , Monica Di Paola +6 more

Gut microbial composition depends on different dietary habits just as health depends on microbial metabolism, but the association of microbiota with different diets in human pop...

2010 Proceedings of the National Academy o... 5426 citations

Diet rapidly and reproducibly alters the human gut microbiome

Lawrence A. David , Corinne F. Maurice , Rachel N. Carmody +10 more

2013 Nature 9567 citations

Reduced Dietary Intake of Carbohydrates by Obese Subjects Results in Decreased Concentrations of Butyrate and Butyrate-Producing Bacteria in Feces

Sylvia H. Duncan , Álvaro Belenguer , Grietje Holtrop +3 more

ABSTRACT Weight loss diets for humans that are based on a high intake of protein but low intake of fermentable carbohydrate may alter microbial activity and bacterial population...

2006 Applied and Environmental Microbiology 932 citations

Publication Info

Year: 2011
Type: article
Volume: 333
Issue: 6038
Pages: 101-104
Citations: 558
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Predicting a Human Gut Microbiota’s Response to Diet in Gnotobiotic Mice

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

558

OpenAlex

Cite This

APA Style

                            
                                
                                    Jeremiah J. Faith, 
                                
                                    Nathan P. McNulty, 
                                
                                    Federico E. Rey
                                
                                et al.
                            
                            (2011). 
                            Predicting a Human Gut Microbiota’s Response to Diet in Gnotobiotic Mice. 
                            Science
                            , 333
                            (6038)
                            , 101-104.
                            https://doi.org/10.1126/science.1206025
                        

Identifiers

DOI: 10.1126/science.1206025