Practical Process Research & Development

Neal G. Anderson

Abstract

Foreword by K. Barry Sharpless. Foreword by Jerome L. Moniot. Preface. About the Author. Approaches to Process Development. Route Selection. Reagent Selection. Solvent Selection. Running the Reaction. Effects of Water. In-Process Controls. Optimizing the Reaction by Minimizing Impurities. Optimizing Catalytic Reactions. Work-Up. Tools for Purifying the Product: Column Chromatography, Crystallization, and Reslurrying. Final Product Form and Impurity Considerations. Vessels and Mixing. Preparing for and Implementing the Scale-up Run. Troubleshooting. Chiral Syntheses. General Index. Reaction Type Index. Reagent Index.

Keywords

TroubleshootingReagentProcess developmentSolventSelection (genetic algorithm)Process (computing)Process engineeringImpurityChemistryWork (physics)ChromatographyCatalysisCrystallizationIndex (typography)Scale (ratio)Computer scienceCombinatorial chemistryOrganic chemistryEngineeringArtificial intelligencePhysicsMechanical engineering

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Publication Info

Year: 2000
Type: book
Citations: 108
Access: Closed

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                                    Neal G. Anderson
                                
                            (2000). 
                            Practical Process Research & Development. 
                            Medical Entomology and Zoology
                            
                            .