Potent antiretroviral treatment of HIV-infection results in suppression of the seminal shedding of HIV

Abstract

In patients with treatment-induced suppression of blood viral load the likelihood of having detectable HIV in semen is very low (< 4%). In addition, seminal shedding of cell-free and cell-associated HIV is significantly lower than in an untreated population of HIV-infected asymptomatic men. On a population basis, this effect of therapy may help to reduce sexual transmission of HIV. However, individual patients may still be infected as evidenced by continued shedding of cells harbouring the HIV provirus.

Keywords

SemenViral loadAsymptomaticMedicineOdds ratioPopulationImmunologyLentivirusSidaViral diseaseInternal medicineHuman immunodeficiency virus (HIV)VirologyBiologyAndrology

MeSH Terms

Anti-HIV AgentsCohort StudiesDNAViralHIVHIV InfectionsHumansMalePolymerase Chain ReactionProvirusesRNAViralReagent KitsDiagnosticSemenViral Load

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Publication Info

Year: 2000
Type: article
Volume: 14
Issue: 2
Pages: 117-121
Citations: 273
Access: Closed

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APA Style

                            
                                
                                    Pietro Vernazza, 
                                
                                    Luigi Troiani, 
                                
                                    Markus Flepp
                                
                                et al.
                            
                            (2000). 
                            Potent antiretroviral treatment of HIV-infection results in suppression of the seminal shedding of HIV. 
                            AIDS
                            , 14
                            (2)
                            , 117-121.
                            https://doi.org/10.1097/00002030-200001280-00006
                        

Identifiers

DOI: 10.1097/00002030-200001280-00006
PMID: 10708281

Data Quality

Data completeness: 86%