Abstract

We confirm the early decline of HPV infection with age but note increased prevalence after menopause, which could be related to a second peak of HSILs, an observation that warrants further investigation. At least 80% of HPVs involved in cervical carcinogenesis in this population have been characterized. Polyvalent vaccines including the main cancer-associated HPV types may be able to prevent most cases of cervical disease in this region.

Keywords

MedicineHPV infectionPopulationOdds ratioCervical cancerCervixConfidence intervalGynecologyObstetricsCancerInternal medicine

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Publication Info

Year
2000
Type
article
Volume
92
Issue
6
Pages
464-474
Citations
596
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Closed

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Rolando Herrero, Allan Hildesheim, Concepción Bratti et al. (2000). Population-Based Study of Human Papillomavirus Infection and Cervical Neoplasia in Rural Costa Rica. JNCI Journal of the National Cancer Institute , 92 (6) , 464-474. https://doi.org/10.1093/jnci/92.6.464

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DOI
10.1093/jnci/92.6.464