Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial

Kohei Shitara , Mustafa Özgüroğlu , Yung‐Jue Bang , Kohei Shitara , Mustafa Özgüroğlu , Yung‐Jue Bang , Maria Di Bartolomeo , Mario Mandalà , Min‐Hee Ryu , Lorenzo Fornaro , Tomasz Olesiński , Christian Caglevic , Hyun Cheol Chung , James Lynam , Niall C. Tebbutt , Mark Wong , Andrew Strickland , Christos S. Karapetis , David Goldstein , Paul L. Vasey , Jean–Luc Van Laethem , Eric Van Cutsem , Scott Berry , Mark Vincent , Bettina Müller , Felipe Rey , Ángela R. Zambrano , Joaquín Guerra , Merete Krogh , Lene Bæksgaard , Mette Yilmaz , Anneli Elme , Andrus Magi , Päivi Auvinen , Tuomo Alanko , Markus Moehler , Volker Kunzmann , Thomas Seufferlein , Peter Thuss-Patience , Eray Goekkurt , Thomas Hoehler , Georg Martin Haag , Salah‐Eddin Al‐Batran , Hugo R. Castro , Karla Alejandra Lopez , Mynor Aguilar Vasquez , Mario Sandoval , Ka On Lam , Sinéad Cuffe , Catherine M. Kelly , Ravit Geva , Einat Shacham‐Shmueli , Ayala Hubert , Alex Beny , Baruch Brenner , Giuseppe Aprile , Alfredo Falcone , Evaristo Maiello , Rodolfo Passalacqua , Vincenzo Montesarchio , Hiroki Hara , Keisho Chìn , Tomohiro Nishina , Yoshito Komatsu , Nozumo Machida , Shuichi Hironaka , Taroh Satoh , Takao Tamura , Naotaoshi Sugimoto , Haruhiko Cho , Yashushi Omuro , Ken Kato , Masahiro Goto , Ichinosuke Hyodo , Kazuhiro Yoshida , Hideo Baba , Taito Esaki , Junji Furuse , Wan Zamaniah Wan Mohammed , Carlos Hernández Hernández , Juan Casas Garcia , Adriana Dominguez Andrade , Katriona Clarke , Geir Olav Hjortland , Nils Glenjen , Tomasz Kubiatowski , Jassem Jacek , Marek Z. Wojtukiewicz , Sergey Lazarev , Yuri Lancukhay , Kei Muro , Eray Goekkurt , Wasat Mansoor , Ray McDermott , Einat Shacham‐Shmueli , Xinqun Chen , Carlos Mayo , Soonmo Peter Kang , Atsushi Ohtsu , Charles S. Fuchs , Guillermo Lerzo , Juan Manuel O’Connor , Guillermo Ariel Mendez
2018 The Lancet 1,262 citations

Keywords

MedicinePaclitaxelPembrolizumabGastroesophageal JunctionCancerOpen labelEsophagogastric junctionInternal medicineGastroenterologyRandomized controlled trialSurgeryAdenocarcinomaImmunotherapy

Affiliated Institutions

Related Publications

Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial

Docetaxel-based chemotherapy is effective in metastatic gastric and gastro-oesophageal junction adenocarcinoma. This study reports on the safety and efficacy of the docetaxel-ba...

2019 The Lancet 2355 citations

Publication Info

Year
2018
Type
article
Volume
392
Issue
10142
Pages
123-133
Citations
1262
Access
Closed

External Links

Citation Metrics

1262
OpenAlex

Cite This

Kohei Shitara, Mustafa Özgüroğlu, Yung‐Jue Bang et al. (2018). Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial. The Lancet , 392 (10142) , 123-133. https://doi.org/10.1016/s0140-6736(18)31257-1

Identifiers

DOI
10.1016/s0140-6736(18)31257-1