Parkinson's disease: affection of brain stem nuclei controlling premotor and motor neurons of the somatomotor system

Keywords

NeuroscienceLocus coeruleusRaphe nucleiParkinson's diseaseLimbic systemReticular formationPsychologyBiologyMedicineNucleusCentral nervous systemPathologyDiseaseSerotonergicInternal medicine

Affiliated Institutions

Related Publications

Where Does Parkinson Disease Pathology Begin in the Brain?

Kelly Del Tredici , Udo Rüb , Rob A. I. de Vos +2 more

The substantia nigra is not the induction site in the brain of the neurodegenerative process underlying Parkinson disease (PD). Instead, the results of this semi-quantitative st...

2002 Journal of Neuropathology & Experimen... 771 citations

STRIATONIGRAL DEGENERATION

Julian Fearnley , Andrew J. Lees

The clinical and pathological features of 10 cases of striatonigral degeneration are described: 5 were misdiagnosed in life as Parkinson's disease. Retrospectively, helpful earl...

1990 Brain 288 citations

The substantia nigra of the human brain

Philippe Damier , Étienne C. Hirsch , Yves Agid +1 more

To achieve accuracy in studying the patterns of loss of midbrain dopamine-containing neurons in Parkinson's disease, we used compartmental patterns of calbindin D(28K) immunosta...

1999 Brain 1719 citations

New developments in the pathology of Parkinson's disease.

K. A. Jellinger

Recent data on neuronal cytoskeletal pathology of Lewy bodies, a major anatomical hallmark of PD, suggest pathological phosphorylation of neurofilament proteins with ubiquitinat...

1990 PubMed 102 citations

The substantia nigra of the human brain

Philippe Damier , Étienne C. Hirsch , Yves Agid +1 more

Parkinson's disease is characterized by massive degeneration of dopamine-containing neurons in the midbrain. However, the vulnerability of these neurons is heterogeneous both ac...

1999 Brain 567 citations

Publication Info

Year: 2000
Type: article
Volume: 99
Issue: 5
Pages: 489-495
Citations: 153
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Parkinson's disease: affection of brain stem nuclei controlling premotor and motor neurons of the somatomotor system

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

153

OpenAlex

Cite This

APA Style

                            
                                
                                    Heiko Braak, 
                                
                                    Udo Rüb, 
                                
                                    Daniele Sandmann-Keil
                                
                                et al.
                            
                            (2000). 
                            Parkinson's disease: affection of brain stem nuclei controlling premotor and motor neurons of the somatomotor system. 
                            Acta Neuropathologica
                            , 99
                            (5)
                            , 489-495.
                            https://doi.org/10.1007/s004010051150
                        

Identifiers

DOI: 10.1007/s004010051150