Parkinson disease and smoking revisited

Beate Ritz; Pei‐Chen Lee; Christina Funch Lassen; Onyebuchi A. Arah

doi:10.1212/wnl.0000000000000879

Abstract

Our data support the notion that patients with PD are able to quit smoking more easily than controls. These findings are compatible with a decreased responsiveness to nicotine during the prodromal phase of PD. We propose that ease of smoking cessation is an aspect of premanifest PD similar to olfactory dysfunction, REM sleep disorders, or constipation and suggests that the apparent "neuroprotective" effect of smoking observed in epidemiologic studies is due to reverse causation.

Keywords

MedicineOdds ratioConfoundingNicotineSmoking cessationLogistic regressionPopulationDiseaseParkinson's diseaseConfidence intervalInternal medicineEnvironmental healthPathology

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Publication Info

Year: 2014
Type: article
Volume: 83
Issue: 16
Pages: 1396-1402
Citations: 152
Access: Closed

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APA Style

                            
                                
                                    Beate Ritz, 
                                
                                    Pei‐Chen Lee, 
                                
                                    Christina Funch Lassen
                                
                                et al.
                            
                            (2014). 
                            Parkinson disease and smoking revisited. 
                            Neurology
                            , 83
                            (16)
                            , 1396-1402.
                            https://doi.org/10.1212/wnl.0000000000000879
                        

Identifiers

DOI: 10.1212/wnl.0000000000000879