Abstract
During inflammatory processes biologically active lipid oxidation products accumulate that modulate the inflammatory process and may determine the fate and outcome of the body's reaction in acute inflammation during host defense. Oxidized phospholipids may induce and propagate chronic inflammatory processes; however, evidence is accumulating that cells and tissues respond towards these oxidatively formed stress signals also by activation of anti-inflammatory, cytoprotective reactions.
Keywords
InflammationLipopolysaccharideChemistryTumor necrosis factor alphaImmune systemSignal transductionCell biologyPhospholipidLipid signalingBiochemistryBiologyImmunology
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Publication Info
- Year
- 2003
- Type
- review
- Volume
- 14
- Issue
- 5
- Pages
- 421-430
- Citations
- 289
- Access
- Closed
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Cite This
Norbert Leitinger
(2003).
Oxidized phospholipids as modulators of inflammation in atherosclerosis.
Current Opinion in Lipidology
, 14
(5)
, 421-430.
https://doi.org/10.1097/00041433-200310000-00002
Identifiers
- DOI
- 10.1097/00041433-200310000-00002