Abstract
The complete sequence of the plasmid pHly152-encoded hemolysin (hly) determinant of Escherichia coli is presented and compared with a recently sequenced chromosomal hly determinant [1]. High sequence homology between the two hly determinants is observed withìn all four structural genes, hlyC, A, B and D, but little sequence similarities are found in the 3′- and 5′-noncoding flanking regions. In addition, the noncoding region upstream of hlyC which carries the promoter for hlyC, A and B, was sequenced for several chromosomal hly determinants. The comparison of these sequences indicates three distinct classes of promoter regions which share common putative −10 and −35 boxes at roughly the same location relative to the start of hlyC.
Keywords
GeneticsHemolysinPlasmidBiologyNucleic acid sequenceHomology (biology)GeneSequence (biology)Insertion sequenceEscherichia coliSequence analysisConsensus sequencePeptide sequenceGenomeTransposable elementVirulence
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Publication Info
- Year
- 1986
- Type
- article
- Volume
- 34
- Issue
- 1
- Pages
- 1-11
- Citations
- 158
- Access
- Closed
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Cite This
J Hess,
Winfried S. Wels,
Monika Vogel
et al.
(1986).
Nucleotide sequence of a plasmid-encoded hemolysin determinant and its comparison with a corresponding chromosomal hemolysin sequence.
FEMS Microbiology Letters
, 34
(1)
, 1-11.
https://doi.org/10.1111/j.1574-6968.1986.tb01339.x
Identifiers
- DOI
- 10.1111/j.1574-6968.1986.tb01339.x