Novel Risk Factors for Systemic Atherosclerosis

Abstract

Of 11 atherothrombotic biomarkers assessed at baseline, the total cholesterol-HDL-C ratio and CRP were the strongest independent predictors of development of peripheral arterial disease. C-reactive protein provided additive prognostic information over standard lipid measures.

Keywords

MedicineInternal medicineCholesterolFibrinogenHomocysteineApolipoprotein BProspective cohort studyLipoproteinRisk factorEndocrinologyHigh-density lipoproteinC-reactive proteinRelative riskCohortGastroenterologyUnivariate analysisConfidence intervalMultivariate analysisInflammation

MeSH Terms

AdultAgedApolipoproteinsArteriosclerosisBiomarkersC-Reactive ProteinCase-Control StudiesCholesterolFibrinogenHomocysteineHumansLikelihood FunctionsLipoprotein(a)MaleMiddle AgedPeripheral Vascular DiseasesPredictive Value of TestsProspective StudiesRegression AnalysisRisk FactorsStatisticsNonparametric

Affiliated Institutions

Brigham and Women's Hospital US

Related Publications

Nonalcoholic Fatty Liver, Steatohepatitis, and the Metabolic Syndrome

Giulio Marchesini , Elisabetta Bugianesi , Gabriele Forlani +8 more

Nonalcoholic fatty liver disease (NAFLD) has been associated with the insulin–resistance syndrome, at present defined as the metabolic syndrome, whose limits were recently set. ...

2003 Hepatology 2654 citations

Publication Info

Year: 2001
Type: article
Volume: 285
Issue: 19
Pages: 2481-2481
Citations: 1291
Access: Closed

External Links

View on DOI.org PubMed

Social Impact

Altmetric

Novel Risk Factors for Systemic Atherosclerosis

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

1291

OpenAlex

981

CrossRef

Cite This

APA Style

                            
                                    Paul M. Ridker, 
                                
                                    Meir J. Stampfer, 
                                
                                    Nader Rifai
                                
                            (2001). 
                            Novel Risk Factors for Systemic Atherosclerosis. 
                            JAMA
                            , 285
                            (19)
                            , 2481-2481.
                            https://doi.org/10.1001/jama.285.19.2481

Identifiers

DOI: 10.1001/jama.285.19.2481
PMID: 11368701

Data Quality

Data completeness: 81%