Abstract
Cases of hepatitis virus infection in Japanese recipients of blood transfusions were serologically and clinically analyzed after the introduction of laboratory screening of donor blood for hepatitis B surface antigen by counter immunoelectrophoresis. Non-A, non-B hepatitis occurred in 116 (10.7%) and hepatitis type B in nine (0.9%) of the 1,082 recipients. The incubation period of the post-transfusion non-A, non-B hepatitis cases varied from two to 33 weeks, but most occurred within 15 weeks. In 97 (83.6%) of the 116 cases of non-A, non-B hepatitis studied, the duration of abnormal elevation of the level of serum alanine aminotransferase (glutamic-pyruvic transaminase [SGPT]) was 16 weeks. The cases of non-A, non-B hepatitis could be divided into three groups according to the pattern of elevation of SGPT levels. These findings may suggest either a multiple etiology for non-A, non-B hepatitis or a variety of clinical symptoms with a single etiology for the infection.
Keywords
Sendai virusMedicineFamily medicinePediatricsVirologyVirus
MeSH Terms
Alanine TransaminaseBlood DonorsCounterimmunoelectrophoresisHemagglutination TestsHepatitis BHepatitis B Surface AntigensHepatitisViralHumanHumansJapanTime FactorsTransfusion Reaction
Affiliated Institutions
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Publication Info
- Year
- 1979
- Type
- article
- Volume
- 139
- Issue
- 5
- Pages
- 511-518
- Citations
- 81
- Access
- Closed
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Cite This
A Tateda,
Katsuko Kikuchi,
Yoshio Numazaki
et al.
(1979).
Non-B Hepatitis in Japanese Recipients of Blood Transfusions: Clinical and Serologic Studies after the Introduction of Laboratory Screening of Donor Blood for Hepatitis B Surface Antigen.
The Journal of Infectious Diseases
, 139
(5)
, 511-518.
https://doi.org/10.1093/infdis/139.5.511
Identifiers
- DOI
- 10.1093/infdis/139.5.511
- PMID
- 438550