Nodal Antagonists in the Anterior Visceral Endoderm Prevent the Formation of Multiple Primitive Streaks

Keywords

Primitive streakEndodermNODALBiologyGastrulationNodal signalingCell biologyEmbryonic stem cellEmbryoAnatomyFate mappingEmbryogenesisGeneticsGene

Affiliated Institutions

Related Publications

<i>nodal</i> expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation

Isabelle Varlet , Jérôme Collignon , Elizabeth J. Robertson

ABSTRACT Mouse nodal, a member of the TGFβ family of secreted growth factors is essential for gastrulation. We recently generated a nodallacZ reporter allele by homologous recom...

1997 Development 385 citations

Misexpression of <i>Cwnt8C</i> in the mouse induces an ectopic embryonic axis and causes a truncation of the anterior neuroectoderm

Heike Pöpperl , Christel Schmidt , Valerie Wilson +4 more

ABSTRACT Transgenic embryos expressing Cwnt8C under the control of the human β-actin promoter exhibit duplicated axes or a severely dorsalised phenotype. Although the transgene ...

1997 Development 145 citations

Interactions between Wnt and Vg1 signalling pathways initiate primitive streak formation in the chick embryo

Isaac Skromne , Claudio D. Stern

The posterior marginal zone (PMZ) of the chick embryo has Nieuwkoop centre-like properties: when transplanted to another part of the marginal zone, it induces a complete embryon...

2001 Development 157 citations

Misexpression of chick Vg1 in the marginal zone induces primitive streak formation

Shailan B. Shah , Isaac Skromne , Clifford R. Hume +4 more

ABSTRACT In the chick embryo, the primitive streak is the first axial structure to develop. The initiation of primitive streak formation in the posterior area pellucida is influ...

1997 Development 121 citations

An Overview of Epithelio-Mesenchymal Transformation

Elizabeth D. Hay

Epithelium is the tissue phenotype of early embryos and primitive adults of the chordate phylum. A second tissue type, however, is produced by epithelial-mesenchymal transformat...

1995 Cells Tissues Organs 1535 citations

Publication Info

Year: 2002
Type: article
Volume: 3
Issue: 5
Pages: 745-756
Citations: 391
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Nodal Antagonists in the Anterior Visceral Endoderm Prevent the Formation of Multiple Primitive Streaks

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

391

OpenAlex

Cite This

APA Style

                            
                                
                                    Aitana Perea-Gómez, 
                                
                                    Francis Vella, 
                                
                                    William Shawlot
                                
                                et al.
                            
                            (2002). 
                            Nodal Antagonists in the Anterior Visceral Endoderm Prevent the Formation of Multiple Primitive Streaks. 
                            Developmental Cell
                            , 3
                            (5)
                            , 745-756.
                            https://doi.org/10.1016/s1534-5807(02)00321-0
                        

Identifiers

DOI: 10.1016/s1534-5807(02)00321-0