Abstract
In this paper, we describe decision making procedures as they exist in most clinical trials,review some recently suggested approaches to monitoring and clarify how these methods allow greater flexibility in monitoring and explicit specification of data monitoring methods in the protocol.
Keywords
Flexibility (engineering)Computer scienceTerm (time)Protocol (science)Clinical trialRisk analysis (engineering)Reliability engineeringMedicineEngineeringMathematicsStatistics
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Publication Info
- Year
- 1984
- Type
- article
- Volume
- 13
- Issue
- 19
- Pages
- 2339-2353
- Citations
- 65
- Access
- Closed
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Cite This
K. K. Gordon Lan,
David L. Detlets,
Max Halperin
(1984).
More flexible sequential and non-sequential designs in long-term clinical trial.
Communication in Statistics- Theory and Methods
, 13
(19)
, 2339-2353.
https://doi.org/10.1080/03610928408828830
Identifiers
- DOI
- 10.1080/03610928408828830