Model-based Analysis of ChIP-Seq (MACS)

Keywords

BiologyComputational biologyHuman geneticsGenome BiologyComputational genomicsEvolutionary biologyGenomicsGeneticsGenomeGene

Affiliated Institutions

Related Publications

The Human Genome Project

Eric D. Green , R Waterston

The recently initiated human genome project is a large international effort to elucidate the genetic architecture of the genomes of man and several model organisms. The initial ...

1991 JAMA 35 citations

Genome-Wide Mapping of in Vivo Protein-DNA Interactions

David S. Johnson , A Mortazavi , R Myers +1 more

In vivo protein-DNA interactions connect each transcription factor with its direct targets to form a gene network scaffold. To map these protein-DNA interactions comprehensively...

2007 Science 2914 citations

Mutational Processes Molding the Genomes of 21 Breast Cancers

Serena Nik‐Zainal , Ludmil B. Alexandrov , David C. Wedge +50 more

2012 Cell 1933 citations

Genome-wide identification of chromosomal regions of increased tumor expression by transcriptome analysis.

Yan Zhou , Shiuh-Ming Luoh , Yan Zhang +5 more

Genes up-regulated in tumor cells provide attractive anticancer therapeutic targets. Although the general underlying mechanism for the increased expression in tumors is unknown,...

2003 PubMed 51 citations

PurityEst: estimating purity of human tumor samples using next-generation sequencing data

Xiaoping Su , Li Zhang , Jianping Zhang +2 more

Abstract Summary: We developed a novel algorithm, PurityEst, to infer the tumor purity level from the allelic differential representation of heterozygous loci with somatic mutat...

2012 Bioinformatics 77 citations

Publication Info

Year: 2008
Type: article
Volume: 9
Issue: 9
Pages: R137-R137
Citations: 18663
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Model-based Analysis of ChIP-Seq (MACS)

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

18663

OpenAlex

Cite This

APA Style

                            
                                
                                    Yong Zhang, 
                                
                                    Tao Liu, 
                                
                                    Clifford A. Meyer
                                
                                et al.
                            
                            (2008). 
                            Model-based Analysis of ChIP-Seq (MACS). 
                            Genome biology
                            , 9
                            (9)
                            , R137-R137.
                            https://doi.org/10.1186/gb-2008-9-9-r137
                        

Identifiers

DOI: 10.1186/gb-2008-9-9-r137