Abstract
microRNAs (miRNAs) are small noncoding RNAs that play important roles in posttranscriptional gene regulation. In animal cells, miRNAs regulate their targets by translational inhibition and mRNA destabilization. Here, we review recent work in animal models that provide insight into the diverse roles of miRNAs in vivo.
Keywords
microRNABiologyRegulation of gene expressionComputational biologyCell biologyGene expressionGeneGenetics
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Publication Info
- Year
- 2007
- Type
- review
- Volume
- 23
- Issue
- 1
- Pages
- 175-205
- Citations
- 2663
- Access
- Closed
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Cite This
Natascha Bushati,
Stephen M. Cohen
(2007).
microRNA Functions.
Annual Review of Cell and Developmental Biology
, 23
(1)
, 175-205.
https://doi.org/10.1146/annurev.cellbio.23.090506.123406
Identifiers
- DOI
- 10.1146/annurev.cellbio.23.090506.123406