Metagenomic Nanopore Sequencing of Influenza Virus Direct from Clinical Respiratory Samples

Abstract

Influenza is a major global public health threat as a result of its highly pathogenic variants, large zoonotic reservoir, and pandemic potential. Metagenomic viral sequencing offers the potential for a diagnostic test for influenza virus which also provides insights on transmission, evolution, and drug resistance and simultaneously detects other viruses. We therefore set out to apply the Oxford Nanopore Technologies sequencing method to metagenomic sequencing of respiratory samples.

Keywords

MetagenomicsBiologyPandemicVirologyInfluenza A virusVirusComputational biologyNanopore sequencingDNA sequencingCoronavirus disease 2019 (COVID-19)Infectious disease (medical specialty)GeneticsGeneMedicineDisease

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Publication Info

Year: 2019
Type: article
Volume: 58
Issue: 1
Citations: 161
Access: Closed

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APA Style

                            
                                
                                    Kuiama Lewandowski, 
                                
                                    Yifei Xu, 
                                
                                    Steven T. Pullan
                                
                                et al.
                            
                            (2019). 
                            Metagenomic Nanopore Sequencing of Influenza Virus Direct from Clinical Respiratory Samples. 
                            Journal of Clinical Microbiology
                            , 58
                            (1)
                            .
                            https://doi.org/10.1128/jcm.00963-19
                        

Identifiers

DOI: 10.1128/jcm.00963-19