Abstract

In a large cohort of strictly defined metabolically healthy men and women, overweight and obesity were strongly and progressively associated with an increased incidence of NAFLD, suggesting that the obese phenotype per se, regardless of metabolic abnormalities, can increase the risk of NAFLD.

Keywords

MedicineNonalcoholic fatty liver diseaseOverweightInternal medicineObesityHazard ratioBody mass indexCohortInsulin resistanceMetabolic syndromeFatty liverIncidence (geometry)Cohort studyType 2 diabetesConfidence intervalHomeostatic model assessmentEndocrinologyGastroenterologyDiabetes mellitusDisease

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Related Publications

The diagnosis and management of non-alcoholic fatty liver disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association

These recommendations are based on the following: (1) a formal review and analysis of the recently published world literature on the topic [Medline search up to June 2011]; (2) ...

2012 Hepatology 3765 citations

Publication Info

Year
2016
Type
article
Volume
111
Issue
8
Pages
1133-1140
Citations
207
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Closed

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Cite This

Yoosoo Chang, Hyun Suk Jung, Juhee Cho et al. (2016). Metabolically Healthy Obesity and the Development of Nonalcoholic Fatty Liver Disease. The American Journal of Gastroenterology , 111 (8) , 1133-1140. https://doi.org/10.1038/ajg.2016.178

Identifiers

DOI
10.1038/ajg.2016.178