Abstract

Membrane lipids form precursors for second messengers and functional assembly matrices on membrane domains during cellular stimulation. Many of these modifications are rapid reactions at lipid headgroups. Metabolism of the fatty acyl portion of membrane lipids leads to the generation of a bewildering complexity of lipid mediators with extended effects in space and time.

Keywords

Lipid metabolismLipid signalingSignal transductionCell signalingMembrane lipidsCell biologySphingolipidBiologySecond messenger systemBiochemistryChemistryMembraneReceptor

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Year
2007
Type
review
Volume
18
Issue
2
Pages
121-128
Citations
160
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Aaron Z. Fernandis, Markus R. Wenk (2007). Membrane lipids as signaling molecules. Current Opinion in Lipidology , 18 (2) , 121-128. https://doi.org/10.1097/mol.0b013e328082e4d5

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DOI
10.1097/mol.0b013e328082e4d5