Mechanisms of NAFLD development and therapeutic strategies

Keywords

Nonalcoholic fatty liver diseaseMedicineCirrhosisMetabolic syndromeClinical trialFatty liverDrugDrug developmentDiseaseDiabetes mellitusNonalcoholic steatohepatitisChronic liver diseaseInternal medicineBioinformaticsLiver diseaseSteatohepatitisIntensive care medicinePharmacologyObesityBiologyEndocrinology

Affiliated Institutions

Related Publications

Update on Nonalcoholic Fatty Liver Disease

Arthur J. McCullough

Nonalcoholic fatty liver disease is now recognized as the most common liver disease in the United States, with a prevalence of approximately 5% in the general population and up ...

2002 Journal of Clinical Gastroenterology 318 citations

Nonalcoholic Steatohepatitis

Elizabeth M. Brunt

Nonalcoholic fatty liver disease (NAFLD) is being increasingly recognized as a common liver disorder that represents the hepatic manifestation of the metabolic syndrome, a varia...

2004 Seminars in Liver Disease 477 citations

Nonalcoholic Fatty Liver, Steatohepatitis, and the Metabolic Syndrome

Giulio Marchesini , Elisabetta Bugianesi , Gabriele Forlani +8 more

Nonalcoholic fatty liver disease (NAFLD) has been associated with the insulin–resistance syndrome, at present defined as the metabolic syndrome, whose limits were recently set. ...

2003 Hepatology 2654 citations

Global epidemiology of nonalcoholic fatty liver disease—Meta‐analytic assessment of prevalence, incidence, and outcomes

Zobair M. Younossi , Aaron B. Koenig , Dinan Abdelatif +3 more

Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver disease worldwide. We estimated the global prevalence, incidence, progression, and outcomes of NAFLD and nonal...

2015 Hepatology 10233 citations

Nonalcoholic Fatty Liver Disease

Giulio Marchesini , Mara Brizi , Giampaolo Bianchi +7 more

Insulin sensitivity (euglycemic clamp, insulin infusion rate: 40 mU · m−2 · min−1) was studied in 30 subjects with biopsy-proven nonalcoholic fatty liver disease (NAFLD), normal...

2001 Diabetes 2558 citations

Publication Info

Year: 2018
Type: review
Volume: 24
Issue: 7
Pages: 908-922
Citations: 3869
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Mechanisms of NAFLD development and therapeutic strategies

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

3869

OpenAlex

Cite This

APA Style

                            
                                
                                    Scott L. Friedman, 
                                
                                    Brent A. Neuschwander‐Tetri, 
                                
                                    Mary E. Rinella
                                
                                et al.
                            
                            (2018). 
                            Mechanisms of NAFLD development and therapeutic strategies. 
                            Nature Medicine
                            , 24
                            (7)
                            , 908-922.
                            https://doi.org/10.1038/s41591-018-0104-9
                        

Identifiers

DOI: 10.1038/s41591-018-0104-9