Mechanisms of Acute Coronary Syndromes and Their Implications for Therapy

2013 New England Journal of Medicine 1,207 citations

Abstract

The notion that heart attacks develop from coronary-artery stenosis is an oversimplification of a process involving lipid metabolism, inflammation, macrophage activation, collagen breakdown, and plaque rupture. These insights are leading to new ideas for treatment and prevention.

Keywords

MedicineInflammationCardiologyMacrophageStenosisInternal medicineIntensive care medicine

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Publication Info

Year
2013
Type
review
Volume
368
Issue
21
Pages
2004-2013
Citations
1207
Access
Closed

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Peter Libby (2013). Mechanisms of Acute Coronary Syndromes and Their Implications for Therapy. New England Journal of Medicine , 368 (21) , 2004-2013. https://doi.org/10.1056/nejmra1216063

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DOI
10.1056/nejmra1216063