Mechanisms Involved in Alleviation of Intestinal Inflammation by Bifidobacterium Breve Soluble Factors

Abstract

Bb and secreted soluble factors contribute positively to intestinal homeostasis by attenuating chemokine production. The results indicate that Bb down regulate inflammation at the epithelial level by inhibiting phosphorylations involved in inflammatory processes and by protective conditioning of dendritic cells.

Keywords

ChemokineSecretionBifidobacterium breveInflammationIntestinal epitheliumInterleukin 8Immune systemColitisProinflammatory cytokineCytokineTumor necrosis factor alphaBiologyCell biologyp38 mitogen-activated protein kinasesMicrobiologyImmunologyCXCL10BifidobacteriumChemistryKinaseEpitheliumMAPK/ERK pathwayBacteriaLactobacillusBiochemistry

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Publication Info

Year: 2009
Type: article
Volume: 4
Issue: 4
Pages: e5184-e5184
Citations: 108
Access: Closed

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APA Style

                            
                                
                                    Élise Heuvelin, 
                                
                                    Corinne Lebreton, 
                                
                                    Corinne Grangette
                                
                                et al.
                            
                            (2009). 
                            Mechanisms Involved in Alleviation of Intestinal Inflammation by Bifidobacterium Breve Soluble Factors. 
                            PLoS ONE
                            , 4
                            (4)
                            , e5184-e5184.
                            https://doi.org/10.1371/journal.pone.0005184
                        

Identifiers

DOI: 10.1371/journal.pone.0005184