Management of hypertension in COVID-19

Abstract

The ACE2 receptor plays a central role in severe acute respiratory syndrome coronavirus 2 host cell entry and propagation. It has therefore been postulated that angiotensin converting enzyme inhibitors and angiotensin receptor blockers may upregulate ACE2 expression and thus increase susceptibility to infection. We suggest that alternative anti-hypertensive agents should be preferred among individuals who may be exposed to this increasingly common and potentially lethal virus.

Keywords

MedicineDownregulation and upregulationCoronavirus disease 2019 (COVID-19)ReceptorAngiotensin-converting enzyme 2CoronavirusAngiotensin Receptor BlockersSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Angiotensin IIRenin–angiotensin systemPharmacologyVirusImmunologyBioinformaticsVirologyInternal medicineBlood pressureBiologyGeneDiseaseBiochemistry

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Publication Info

Year: 2020
Type: article
Volume: 12
Issue: 5
Pages: 228-230
Citations: 13
Access: Closed

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APA Style

                            
                                
                                    Daniel Antwi‐Amoabeng, 
                                
                                    Bryce D. Beutler, 
                                
                                    Alastair E. Moody
                                
                                et al.
                            
                            (2020). 
                            Management of hypertension in COVID-19. 
                            World Journal of Cardiology
                            , 12
                            (5)
                            , 228-230.
                            https://doi.org/10.4330/wjc.v12.i5.228
                        

Identifiers

DOI: 10.4330/wjc.v12.i5.228