Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

2002 Nature Medicine 725 citations

Keywords

LungFetusRespiratory distressMedicineVascular endothelial growth factorHypoxia (environmental)Hypoxia-inducible factorsPulmonary surfactantDownregulation and upregulationInternal medicineEndocrinologyImmunologyAndrologyVEGF receptorsBiologyChemistryAnesthesiaPregnancy

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Year
2002
Type
article
Volume
8
Issue
7
Pages
702-710
Citations
725
Access
Closed

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Veerle Compernolle, Koen Brusselmans, Till Acker et al. (2002). Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nature Medicine , 8 (7) , 702-710. https://doi.org/10.1038/nm721

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DOI
10.1038/nm721