Leukemia and the disruption of normal hematopoiesis

Keywords

BiologyLeukemiaHaematopoiesisCell biologyCancer researchComputational biologyGeneticsStem cell

Affiliated Institutions

Related Publications

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Jinghui Zhang , Li Ding , Linda Holmfeldt +66 more

Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole-genome sequencing of 12 ETP ALL cases and...

2012 Nature 1596 citations

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes

Siddhartha Jaiswal , Pierre Fontanillas , Jason Flannick +31 more

Age-related clonal hematopoiesis is a common condition that is associated with increases in the risk of hematologic cancer and in all-cause mortality, with the latter possibly d...

2014 New England Journal of Medicine 4444 citations

Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

Giulio Genovese , Anna K. Kähler , Robert E. Handsaker +20 more

Clonal hematopoiesis with somatic mutations is readily detected by means of DNA sequencing, is increasingly common as people age, and is associated with increased risks of hemat...

2014 New England Journal of Medicine 3300 citations

Spleen colony studies of leukemia L1210. 3. Differential sensitivities of normal hematopoietic and resistant L1210 colony-forming cells to 6-mercaptopurine (NSC-755).

I Wodinsky , J Swiniarski , Kensler Cj

1968 PubMed 12 citations

Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

Allen Eng Juh Yeoh , Mary Elizabeth Ross , Sheila Shurtleff +18 more

2002 Cancer Cell 1912 citations

Publication Info

Year: 1991
Type: review
Volume: 64
Issue: 2
Pages: 337-350
Citations: 351
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Leukemia and the disruption of normal hematopoiesis

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

351

OpenAlex

Cite This

APA Style

                            
                                    Charles L. Sawyers, 
                                
                                    Christopher T. Denny, 
                                
                                    Owen N. Witte
                                
                            (1991). 
                            Leukemia and the disruption of normal hematopoiesis. 
                            Cell
                            , 64
                            (2)
                            , 337-350.
                            https://doi.org/10.1016/0092-8674(91)90643-d

Identifiers

DOI: 10.1016/0092-8674(91)90643-d