Lack of Effect of Long-Term Supplementation with Beta Carotene on the Incidence of Malignant Neoplasms and Cardiovascular Disease

Charles H. Hennekens; Julie E. Buring; JoAnn E. Manson; Meir J. Stampfer; Bernard Rosner; Nancy R. Cook; Charlene Belanger; Frances LaMotte; J. Michael Gaziano; Paul M. Ridker; Walter C. Willett; Richard Peto

doi:10.1056/nejm199605023341801

Abstract

In this trial among healthy men, 12 years of supplementation with beta carotene produced neither benefit nor harm in terms of the incidence of malignant neoplasms, cardiovascular disease, or death from all causes.

Keywords

MedicinePlaceboIncidence (geometry)Internal medicineCancerObservational studyRelative riskDiseaseClinical trialSkin cancerRandomized controlled trialbeta-CaroteneConfidence intervalCancer preventionSurgeryVitaminPathology

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Publication Info

Year: 1996
Type: article
Volume: 334
Issue: 18
Pages: 1145-1149
Citations: 2403
Access: Closed

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APA Style

                            
                                
                                    Charles H. Hennekens, 
                                
                                    Julie E. Buring, 
                                
                                    JoAnn E. Manson
                                
                                et al.
                            
                            (1996). 
                            Lack of Effect of Long-Term Supplementation with Beta Carotene on the Incidence of Malignant Neoplasms and Cardiovascular Disease. 
                            New England Journal of Medicine
                            , 334
                            (18)
                            , 1145-1149.
                            https://doi.org/10.1056/nejm199605023341801
                        

Identifiers

DOI: 10.1056/nejm199605023341801