Human iPSC-derived microglia carrying LRRK2-G2019 mutation show Parkinson's disease related transcriptional profile and functions

Giudice Luca

doi:10.5281/zenodo.7803015

Abstract

This repository contains the data and the code used in Ohtone Sohvi's project. A folder can contain the starting raw data in "data", the R scripts in order of execution (op1, op2 ..) and the "output" folder that contains the final processed data of each operation. "PD_bulk_analysis" contains the processing and analysis of the bulk RNA sequencing data "PD_bulk_fastq" contains the raw fastq sequences of the bulk RNA sequencing "PD_bulk_nfcore" contains the results of processing the fasta sequences with nfcore rnaseq workflow "PD_scRNA_analysis" contains the analysis of the snRNA sequencing dataset "PD_spatial" contains the raw data of the spatial sequencing, the assempbly of the spatial expression profiles starting from the DAPI images and the transcripts coordinates, the analysis performed on the data

Keywords

LRRK2MicrogliaParkinson's diseaseNeuroscienceDiseaseMutationBiologyMedicineGeneticsGenePathologyImmunologyInflammation

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Publication Info

Year: 2027
Type: dataset
Citations: 0
Access: Closed

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APA Style

                            
                                    Giudice Luca
                                
                            (2027). 
                            Human iPSC-derived microglia carrying LRRK2-G2019 mutation show Parkinson's disease related transcriptional profile and functions. 
                            Zenodo (CERN European Organization for Nuclear Research)
                            
                            .
                            https://doi.org/10.5281/zenodo.7803015

Identifiers

DOI: 10.5281/zenodo.7803015