Abstract
Abstract. A new method of C 3 type determination on high voltage agarose gel electrophoresis is described. The influence of some electrophoretic variables on the results has been investigated and a standard technique developed. The method is quick, simple and gives good separation of C 3 proteins. The three common C 3 phenotypes and the four variant types so far studied are easily demonstrated. Preliminary allele frequencies in a Norwegian population sample is presented. The values found, C 3 S = 0.80 and C 3 F = 0.19, are in good accordance with the allele frequencies in two population groups of North American Caucasians.
Keywords
Agarose gel electrophoresisAgaroseAllele frequencyElectrophoresisPolymorphism (computer science)AlleleChromatographyPopulationMolecular biologyGeneticsBiologyChemistryMedicineDNAGene
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Publication Info
- Year
- 1970
- Type
- article
- Volume
- 19
- Issue
- 1
- Pages
- 47-56
- Citations
- 184
- Access
- Closed
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Cite This
P. Teisberg
(1970).
High Voltage Agarose Gel Electrophoresis in the Study of C 3 Polymorphism.
Vox Sanguinis
, 19
(1)
, 47-56.
https://doi.org/10.1111/j.1423-0410.1970.tb01494.x
Identifiers
- DOI
- 10.1111/j.1423-0410.1970.tb01494.x