Abstract
Many bacterial clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) systems employ the dual RNA–guided DNA endonuclease Cas9 to defend against invading phages and conjugative plasmids by introducing site-specific ...Read More
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Publication Info
- Year
- 1994
- Type
- review
- Volume
- 23
- Issue
- 1
- Pages
- 541-576
- Citations
- 257
- Access
- Closed
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Identifiers
- DOI
- 10.1146/annurev.bb.23.060194.002545