Abstract

Many bacterial clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) systems employ the dual RNA–guided DNA endonuclease Cas9 to defend against invading phages and conjugative plasmids by introducing site-specific ...Read More

Keywords

CRISPRPalindromePlasmidCas9DNAEndonucleaseBiologyGeneticsComputational biologyGene

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Publication Info

Year
1994
Type
review
Volume
23
Issue
1
Pages
541-576
Citations
257
Access
Closed

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Sergei M. Mirkin, M. D. Frank-Kamenet︠s︡kiĭ (1994). H-DNA and Related Structures. Annual Review of Biophysics and Biomolecular Structure , 23 (1) , 541-576. https://doi.org/10.1146/annurev.bb.23.060194.002545

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DOI
10.1146/annurev.bb.23.060194.002545