Abstract

Significance Antibiotic resistance, driven by antibiotic consumption, is a growing global health threat. Our report on antibiotic use in 76 countries over 16 years provides an up-to-date comprehensive assessment of global trends in antibiotic consumption. We find that the antibiotic consumption rate in low- and middle-income countries (LMICs) has been converging to (and in some countries surpassing) levels typically observed in high-income countries. However, inequities in drug access persist, as many LMICs continue to be burdened with high rates of infectious disease-related mortality and low rates of antibiotic consumption. Our findings emphasize the need for global surveillance of antibiotic consumption to support policies to reduce antibiotic consumption and resistance while providing access to these lifesaving drugs.

Keywords

Consumption (sociology)AntibioticsAntibiotic resistanceEnvironmental healthGlobal healthConvergence (economics)MedicinePublic healthBusinessEconomic growthEconomicsBiologyPathologyMicrobiology

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Publication Info

Year
2018
Type
article
Volume
115
Issue
15
Pages
E3463-E3470
Citations
2985
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Closed

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Eili Klein, Thomas P. Van Boeckel, Elena Martínez et al. (2018). Global increase and geographic convergence in antibiotic consumption between 2000 and 2015. Proceedings of the National Academy of Sciences , 115 (15) , E3463-E3470. https://doi.org/10.1073/pnas.1717295115

Identifiers

DOI
10.1073/pnas.1717295115