Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes

Angli Xue , Yang Wu , Zhihong Zhu , Angli Xue , Yang Wu , Zhihong Zhu , Futao Zhang , Kathryn E. Kemper , Zhili Zheng , Loïc Yengo , Luke R. Lloyd‐Jones , Julia Sidorenko , Yeda Wu , Mawussé Agbessi , Habibul Ahsan , Isabel Alves , Anand Kumar Andiappan , Philip Awadalla , Alexis Battle , Frank Beutner , Marc Jan Bonder , Dorret I. Boomsma , Mark Christiansen , Annique Claringbould , Patrick Deelen , Tõnu Esko , Marie-Julie Favé , Lude Franke , Timothy M. Frayling , Sina A. Gharib , Gregory Gibson , Gibran Hemani , Rick Jansen , Mika Kähönen , Anette Kalnapenkis , Silva Kasela , Johannes Kettunen , Yungil Kim , Holger Kirsten , Péter Kovács , Knut Krohn , Jaanika Kronberg-Guzman , Viktorija Kukushkina , Zoltán Kutalik , Bernett Lee , Terho Lehtimäki , Markus Loeffler , Urko M. Marigorta , Andres Metspalu , Lili Milani , Martina Müller‐Nurasyid , Matthias Nauck , Michel G. Nivard , Brenda W.J.H. Penninx , Markus Perola , Natalia Pervjakova , Brandon L. Pierce , Joseph E. Powell , Holger Prokisch , Bruce M. Psaty , Olli T. Raitakari , Susan M. Ring , Samuli Ripatti , Olaf Rötzschke , Sina Rüeger , Ashis Saha , Markus Scholz , Katharina Schramm , Ilkka Seppälä , Michael Stümvoll , Patrick Sullivan , Alexander Teumer , Joachim Thiery , Tong Lin , Anke Tönjes , Jenny van Dongen , Joyce B. J. van Meurs , Joost Verlouw , Uwe Völker , Urmo Võsa , Hanieh Yaghootkar , Biao Zeng , Allan F. McRae , Peter M. Visscher , Jian Zeng , Jian Yang
2018 Nature Communications 974 citations

Keywords

Genome-wide association studyBiologyEpigenomicsGeneticsDNA methylationGenetic associationExpression quantitative trait lociEpigeneticsGeneComputational biologyType 2 diabetesGenomeSingle-nucleotide polymorphismGene expressionGenotypeDiabetes mellitus

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Year
2018
Type
review
Volume
9
Issue
1
Pages
2941-2941
Citations
974
Access
Closed

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Angli Xue, Yang Wu, Zhihong Zhu et al. (2018). Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. Nature Communications , 9 (1) , 2941-2941. https://doi.org/10.1038/s41467-018-04951-w

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DOI
10.1038/s41467-018-04951-w