Genome 10K: A Proposal to Obtain Whole-Genome Sequence for 10 000 Vertebrate Species

Abstract

The human genome project has been recently complemented by whole-genome assessment sequence of 32 mammals and 24 nonmammalian vertebrate species suitable for comparative genomic analyses. Here we anticipate a precipitous drop in costs and increase in sequencing efficiency, with concomitant development of improved annotation technology and, therefore, propose to create a collection of tissue and DNA specimens for 10,000 vertebrate species specifically designated for whole-genome sequencing in the very near future. For this purpose, we, the Genome 10K Community of Scientists (G10KCOS), will assemble and allocate a biospecimen collection of some 16,203 representative vertebrate species spanning evolutionary diversity across living mammals, birds, nonavian reptiles, amphibians, and fishes (ca. 60,000 living species). In this proposal, we present precise counts for these 16,203 individual species with specimens presently tagged and stipulated for DNA sequencing by the G10KCOS. DNA sequencing has ushered in a new era of investigation in the biological sciences, allowing us to embark for the first time on a truly comprehensive study of vertebrate evolution, the results of which will touch nearly every aspect of vertebrate biological enquiry.

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Affiliated Institutions

• University of California, Berkeley US
• Texas A&M University US
• University College Dublin IE
• George Washington University US
• Villanova University US
• University of Guelph CA
• Monterey Bay Aquarium Research Institute US
• University of California, Los Angeles US
• Agency for Science, Technology and Research SG
• Universidad de Los Andes CO
• Louisiana State University US
• University of Bedfordshire GB
• American Museum of Natural History US
• University of Montana US
• Australian National University AU
• Fundação Oswaldo Cruz BR
• University of California, Davis US
• University of Kansas US
• Smithsonian Institution US
• Novosibirsk State University RU
• Broad Institute US
• Harvard University Press US
• University of Copenhagen DK
• Kunming Institute of Zoology CN
• University of Nottingham GB
• University of California, Riverside US
• Oregon State University US
• Science Applications International Corporation (United States) US
• National Institutes of Health US
• Health Sciences and Nutrition AU
• Universidade do Porto PT
• University of Illinois Urbana-Champaign US
• University of California, Santa Cruz US
• Pennsylvania State University US
• Stanford University US
• Okinawa Institute of Science and Technology Graduate University JP
• Universidade Federal do Rio de Janeiro BR
• Max Planck Society DE
• Washington University in St. Louis US
• Max Planck Innovation DE
• University of Sheffield GB
• Commonwealth Scientific and Industrial Research Organisation AU

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