Frailty in Older Adults: Evidence for a Phenotype

Abstract

This study provides a potential standardized definition for frailty in community-dwelling older adults and offers concurrent and predictive validity for the definition. It also finds that there is an intermediate stage identifying those at high risk of frailty. Finally, it provides evidence that frailty is not synonymous with either comorbidity or disability, but comorbidity is an etiologic risk factor for, and disability is an outcome of, frailty. This provides a potential basis for clinical assessment for those who are frail or at risk, and for future research to develop interventions for frailty based on a standardized ascertainment of frailty.

Keywords

MedicineComorbidityConcordanceGerontologyCohortGrip strengthPopulationCohort studyIncidence (geometry)DiseaseDemographyPhysical therapyInternal medicineEnvironmental health

Affiliated Institutions

Johns Hopkins University US

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Publication Info

Year: 2001
Type: article
Volume: 56
Issue: 3
Pages: M146-M157
Citations: 22987
Access: Closed

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Cite This

APA Style

                            
                                
                                    Linda P. Fried, 
                                
                                    Catherine M. Tangen, 
                                
                                    Jeremy Walston
                                
                                et al.
                            
                            (2001). 
                            Frailty in Older Adults: Evidence for a Phenotype. 
                            The Journals of Gerontology Series A
                            , 56
                            (3)
                            , M146-M157.
                            https://doi.org/10.1093/gerona/56.3.m146
                        

Identifiers

DOI: 10.1093/gerona/56.3.m146