Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

Nathalie Q. Balaban; Ulrich S. Schwarz; Daniel Riveline; Polina Goichberg; Gila Tzur; Ilana Sabanay; D. Mahalu; S. A. Safran; Alexander D. Bershadsky; Lia Addadi; Benjamin Geiger

doi:10.1038/35074532

Keywords

Focal adhesionVinculinMicropatterningAdhesionCytoskeletonBiophysicsPaxillinContractilityMechanotransductionActinChemistryMaterials scienceNanotechnologyCell biologyCellBiologyComposite materialBiochemistry

Affiliated Institutions

Related Publications

FOCAL ADHESIONS, CONTRACTILITY, AND SIGNALING

Keith Burridge , Magdalena Chrzanowska‐Wodnicka

▪ Abstract Focal adhesions are sites of tight adhesion to the underlying extracellular matrix developed by cells in culture. They provide a structural link between the actin cyt...

1996 Annual Review of Cell and Development... 1951 citations

Integrins and Actin Filaments: Reciprocal Regulation of Cell Adhesion and Signaling

David Calderwood , Sanford J. Shattil , Mark H. Ginsberg

extracellular matrix focal adhesions ezrin, radixin, and moesin vasodilator-stimulated phosphoprotein Wiskott-Aldrich syndrome protein integrin-linked kinase Integrin adhesion r...

2000 Journal of Biological Chemistry 505 citations

Imaging Intracellular Fluorescent Proteins at Nanometer Resolution

Eric Betzig , George H. Patterson , Rachid Sougrat +6 more

We introduce a method for optically imaging intracellular proteins at nanometer spatial resolution. Numerous sparse subsets of photoactivatable fluorescent protein molecules wer...

2006 Science 8649 citations

Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion

Shuh Narumiya , Masahiro Tanji , Toshimasa Ishizaki

The Rho subgroup of the Rho GTPases consisting of RhoA, RhoB and RhoC induces a specific type of actin cytoskeleton and carry out a variety of functions in the cell. mDia and RO...

2009 Cancer and Metastasis Reviews 527 citations

Relationships between Rap1b, Affinity Modulation of Integrin αIIbβ3, and the Actin Cytoskeleton

Alessandra Bertoni , Seiji Tadokoro , Koji Eto +4 more

The affinity of integrin alpha(IIb)beta(3) for fibrinogen is controlled by inside-out signals that are triggered by agonists like thrombin. Agonist treatment of platelets also a...

2002 Journal of Biological Chemistry 182 citations

Publication Info

Year: 2001
Type: article
Volume: 3
Issue: 5
Pages: 466-472
Citations: 2101
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

2101

OpenAlex

Cite This

APA Style

                            
                                
                                    Nathalie Q. Balaban, 
                                
                                    Ulrich S. Schwarz, 
                                
                                    Daniel Riveline
                                
                                et al.
                            
                            (2001). 
                            Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates. 
                            Nature Cell Biology
                            , 3
                            (5)
                            , 466-472.
                            https://doi.org/10.1038/35074532
                        

Identifiers

DOI: 10.1038/35074532