Abstract

The first external quality assessment MERS-CoV panel gives a good insight in molecular diagnostic techniques and their performances for sensitive and specific detection of MERS-CoV RNA globally. Overall, all laboratories were capable of detecting MERS-CoV with some differences in sensitivity. The observation that 8% of laboratories reported false MERS-CoV positive single assay results shows room for improvement, and the importance of using confirmatory targets.

Keywords

External quality assessmentMiddle East respiratory syndrome coronavirusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Molecular diagnosticsCoronavirus disease 2019 (COVID-19)Medicine2019-20 coronavirus outbreakVirologyComputational biologyBiologyPathologyBioinformaticsDiseaseInfectious disease (medical specialty)

MeSH Terms

Coronavirus InfectionsHumansInternationalityLaboratory Proficiency TestingMiddle East Respiratory Syndrome CoronavirusMolecular Diagnostic TechniquesReal-Time Polymerase Chain ReactionSensitivity and SpecificityViral Load

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Publication Info

Year
2015
Type
article
Volume
69
Pages
81-85
Citations
30
Access
Closed

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Cite This

Suzan D. Pas, Pranav Patel, Chantal Reusken et al. (2015). First international external quality assessment of molecular diagnostics for Mers-CoV. Journal of Clinical Virology , 69 , 81-85. https://doi.org/10.1016/j.jcv.2015.05.022

Identifiers

DOI
10.1016/j.jcv.2015.05.022
PMID
26209385
PMCID
PMC7106520

Data Quality

Data completeness: 86%