Fatigue in Multiple Sclerosis

Lauren Krupp; Lilia Alvarez; Nicholas G. LaRocca; L C Scheinberg

doi:10.1001/archneur.1988.00520280085020

Abstract

Fatigue is a frequent symptom in multiple sclerosis (MS) that can interfere with a patient's daily functioning. The cause of MS fatigue, its clinical characteristics, and its relationship to other symptoms remain poorly understood. Structured interviews were conducted with 32 patients with MS and 33 normal healthy adults. Fatigue proved to be both more frequent and more severe among the patients with MS. Multiple sclerosis fatigue was unrelated to either depression or global impairment. Multiple sclerosis fatigue appears to be a distinct clinical entity, often disabling, that can be distinguished from normal fatigue, affective disturbance, and neurologic impairment.

Keywords

Multiple sclerosisDepression (economics)MedicineChronic fatigue syndromeChronic fatiguePhysical medicine and rehabilitationPhysical therapyPsychologyPsychiatry

MeSH Terms

AdultAttitude to HealthDepressionDiagnosisDifferentialFatigueFemaleHumansMaleMultiple SclerosisNeurologic Examination

Affiliated Institutions

Albert Einstein College of Medicine US

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Publication Info

Year: 1988
Type: article
Volume: 45
Issue: 4
Pages: 435-437
Citations: 980
Access: Closed

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APA Style

                            
                                
                                    Lauren Krupp, 
                                
                                    Lilia Alvarez, 
                                
                                    Nicholas G. LaRocca
                                
                                et al.
                            
                            (1988). 
                            Fatigue in Multiple Sclerosis. 
                            Archives of Neurology
                            , 45
                            (4)
                            , 435-437.
                            https://doi.org/10.1001/archneur.1988.00520280085020
                        

Identifiers

DOI: 10.1001/archneur.1988.00520280085020
PMID: 3355400

Data Quality

Data completeness: 81%