Abstract

Cells are inherently sensitive to local mesoscale, microscale, and nanoscale patterns of chemistry and topography. We review current approaches to control cell behavior through the nanoscale engineering of materials surfaces. Far-reaching implications are emerging for applications including medical implants, cell supports, and materials that can be used as instructive three-dimensional environments for tissue regeneration.

Keywords

Microscale chemistryMesoscale meteorologyNanoscopic scaleNanotechnologyInterface (matter)Surface engineeringRegeneration (biology)Tissue engineeringMaterials scienceEngineeringBiologyGeologyCell biologyBiomedical engineeringComposite material

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Publication Info

Year
2005
Type
review
Volume
310
Issue
5751
Pages
1135-1138
Citations
2569
Access
Closed

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Cite This

Molly M. Stevens, Julian H. George (2005). Exploring and Engineering the Cell Surface Interface. Science , 310 (5751) , 1135-1138. https://doi.org/10.1126/science.1106587

Identifiers

DOI
10.1126/science.1106587