Experiments in molecular genetics

Bioinformatics challenges of new sequencing technology

New DNA sequencing technologies can sequence up to one billion bases in a single day at low cost, putting large-scale sequencing within the reach of many scientists. Many resear...

A gene expression database for the molecular pharmacology of cancer

GOToolBox: functional analysis of gene datasets based on Gene Ontology

Abstract We have developed methods and tools based on the Gene Ontology (GO) resource allowing the identification of statistically over- or under-represented terms in a gene dat...

En Route to Ethical Recommendations for Gene Transfer Clinical Trials

In Geneva, Switzerland, on 2–3 April 2007, Clinigene-NoE (the European Network for the Advancement of Clinical Gene Transfer and Therapy) and Consert (program on Concerted Safet...

Creating the Gene Ontology Resource: Design and Implementation

The exponential growth in the volume of accessible biological information has generated a confusion of voices surrounding the annotation of molecular information about genes and...