Abstract

Abstract Fifteen patients with cirrhosis underwent orthotopic liver transplantation for small hepatocellular carcinoma (HCC) and 12 patients with cirrhosis underwent hepatic resection for similar HCC. All tumours were of the non-fibrolamellar variant. The majority of the patients in the transplant group had Child's grade B or C cirrhosis. Median follow-up was 37 months with a minimum of 18 months. Eleven of 12 patients in the resection group had Child's grade A cirrhosis. Median follow-up was 29 months with a minimum of 16 months. Actuarial survival rates at 1 and 3 years for the transplanted patients were 80 and 63 per cent and all were tumour free. Tumour recurrence rate was 15 per cent. The overall 1- and 3-year tumour-free survival rates for patients in the resection group were 61 and 33 percent. Tumour recurrence rate was 45 percent. The results show orthotopic liver transplantation to be an important surgical option in cirrhotic patients with small HCC, particularly in those with moderate to severe hepatic decompensation.

Keywords

MedicineCirrhosisHepatocellular carcinomaDecompensationLiver transplantationGastroenterologySurvival rateSurgeryTransplantationInternal medicineOrthotopic liver transplantationCarcinomaResection

Affiliated Institutions

Related Publications

Publication Info

Year
1995
Type
article
Volume
82
Issue
2
Pages
253-256
Citations
100
Access
Closed

External Links

View on DOI.org

Social Impact

Altmetric
PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

100
OpenAlex

Cite This

K C Tan, Mohamed Rela, Stephen Ryder et al. (1995). Experience of orthotopic liver transplantation and hepatic resection for hepatocellular carcinoma of less than 8 cm in patients with cirrhosis. British journal of surgery , 82 (2) , 253-256. https://doi.org/10.1002/bjs.1800820239

Identifiers

DOI
10.1002/bjs.1800820239