Exosomes: Mechanisms of Uptake | RDL Research Database

Abstract

Exosomes are 30-100 nm microvesicles which contain complex cellular signals of RNA, protein and lipids. Because of this, exosomes are implicated as having limitless therapeutic potential for the treatment of cancer, pregnancy complications, infections, and autoimmune diseases. To date we know a considerable amount about exosome biogenesis and secretion, but there is a paucity of data regarding the uptake of exosomes by immune and non-immune cell types (e.g., cancer cells) and the internal signalling pathways by which these exosomes elicit a cellular response. Answering these questions is of paramount importance.

Keywords

MicrovesiclesImmune systemExosomeBiogenesisSecretionBiologymicroRNARNACell biologyImmunologyGeneticsGene

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Publication Info

Year: 2015
Type: review
Volume: 4
Pages: 7-7
Citations: 407
Access: Closed

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APA Style

                            
                                    Kelly J. McKelvey, 
                                
                                    Katie Powell, 
                                
                                    Anthony W. Ashton
                                
                                et al.
                            
                            (2015). 
                            Exosomes: Mechanisms of Uptake. 
                            Journal of Circulating Biomarkers
                            , 4
                            
                            , 7-7.
                            https://doi.org/10.5772/61186

Identifiers

DOI: 10.5772/61186