Estimation of the Inbreeding Coefficient through Use of Genomic Data

Anne‐Louise Leutenegger; Bernard Prum; Emmanuelle Génin; Christophe Verny; Arnaud Lemainque; Françoise Clerget‐Darpoux; E. A. Thompson

doi:10.1086/378207

Keywords

Identity by descentInbreedingGeneticsBiologyGenomeLinkage (software)Evolutionary biologyStatisticsAllelePopulationHaplotypeMathematicsGeneDemography

Affiliated Institutions

Related Publications

Does heterozygosity estimate inbreeding in real populations?

François Balloux , William Amos , Tim Coulson

Abstract Many recent studies report that individual heterozygosity at a handful of apparently neutral microsatellite markers is correlated with key components of fitness, with m...

2004 Molecular Ecology 481 citations

Extensive Genome-wide Linkage Disequilibrium in Cattle

Frédéric Farnir , Wouter Coppieters , Juan-José Arranz +12 more

A genome-wide linkage disequilibrium (LD) map was generated using microsatellite genotypes (284 autosomal microsatellite loci) of 581 gametes sampled from the dutch black-and-wh...

2000 Genome Research 351 citations

Efficient Methods to Compute Genomic Predictions

P.M. VanRaden

Efficient methods for processing genomic data were developed to increase reliability of estimated breeding values and to estimate thousands of marker effects simultaneously. Alg...

2008 Journal of Dairy Science 5865 citations

Prediction of Total Genetic Value Using Genome-Wide Dense Marker Maps

T.H.E. Meuwissen , Ben J. Hayes , Michael E. Goddard

Abstract Recent advances in molecular genetic techniques will make dense marker maps available and genotyping many individuals for these markers feasible. Here we attempted to e...

2001 Genetics 7547 citations

Structure of linkage disequilibrium and phenotypic associations in the maize genome

David L. Remington , Jeffry M. Thornsberry , Yoshihiro Matsuoka +6 more

Association studies based on linkage disequilibrium (LD) can provide high resolution for identifying genes that may contribute to phenotypic variation. We report patterns of loc...

2001 Proceedings of the National Academy o... 1250 citations

Publication Info

Year: 2003
Type: article
Volume: 73
Issue: 3
Pages: 516-523
Citations: 286
Access: Closed

External Links

View on DOI.org

Social Impact

Altmetric

Estimation of the Inbreeding Coefficient through Use of Genomic Data

PlumX Metrics

Social media, news, blog, policy document mentions

Citation Metrics

286

OpenAlex

Cite This

APA Style

                            
                                
                                    Anne‐Louise Leutenegger, 
                                
                                    Bernard Prum, 
                                
                                    Emmanuelle Génin
                                
                                et al.
                            
                            (2003). 
                            Estimation of the Inbreeding Coefficient through Use of Genomic Data. 
                            The American Journal of Human Genetics
                            , 73
                            (3)
                            , 516-523.
                            https://doi.org/10.1086/378207
                        

Identifiers

DOI: 10.1086/378207