Abstract

ABSTRACT A distance measure for populations diverging by drift only is based on the coancestry coefficient θ, and three estimators of the distance D = -ln(1 - θ) are constructed for multiallelic, multilocus data. Simulations of a monoecious population mating at random showed that a weighted ratio of single-locus estimators performed better than an unweighted average or a least squares estimator. Jackknifing over loci provided satisfactory variance estimates of distance values. In the drift situation, in which mutation is excluded, the weighted estimator of D appears to be a better measure of distance than others that have appeared in the literature.

Keywords

EstimatorStatisticsBiologyGenetic distanceLocus (genetics)PopulationTerm (time)MathematicsMeasure (data warehouse)Variance (accounting)EconometricsGeneticsGenetic variationComputer scienceDemographyPhysicsGene

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A measure of genetic distance (D) based on the identity of genes between populations is formulated. It is defined as D = -logeI, where I is the normalized identity of genes betw...

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Publication Info

Year
1983
Type
article
Volume
105
Issue
3
Pages
767-779
Citations
1792
Access
Closed

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Cite This

John Reynolds, B. S. Weir, C. Clark Cockerham (1983). ESTIMATION OF THE COANCESTRY COEFFICIENT: BASIS FOR A SHORT-TERM GENETIC DISTANCE. Genetics , 105 (3) , 767-779. https://doi.org/10.1093/genetics/105.3.767

Identifiers

DOI
10.1093/genetics/105.3.767
PMID
17246175
PMCID
PMC1202185

Data Quality

Data completeness: 81%